HueUMP Main Campus
HƯỚNG NGHIÊN CỨU
1. Lĩnh vực Di truyền Y học:
- Di truyền và sản phụ khoa.
- Di truyền và chậm phát triển tâm thần/dị tật bẩm sinh.
- Di truyền và ung thư.
- Yếu tố di truyền người (vật chủ) và vi sinh vật trong các cơ chế và điều trị bệnh.
- Ứng dụng các kỹ thuật sinh học phân tử trong phân tích gene, genome.
2. Lĩnh vực Vi sinh:
- Dịch tễ học phân tử nhiễm trùng các virus cúm và các virus gây nhiễm trùng hô hấp, các Enterovirus gây bệnh tay chân miệng, virus dengue gây sốt xuất huyết, HPV gây ung thư cổ tử cung và u nhú tình dục.
- Dịch tễ học phân tử và chẩn đoán các vi khuẩn gồm vi khuẩn lao (Mycobacteria tuberculosis và lao kháng thuốc, liên cầu lợn (Streptococus suis), chẩn đoán và nghiên cứu đột biến kháng thuốc của các vi khuẩn Helicobacter pylori… chẩn đoán phân tử các Mycoplasma gây nhiễm trùng đường sinh dục.
- Phát triển/Áp dụng các kỹ thuật phân tử để xác định các vi khuẩn và virus nhiễm trùng mới và tái xuất hiện.
- Ứng dụng sinh học phân tử trong định danh loài vi khuẩn bằng kỹ thuật giải trình tự gen và genome vi sinh vật
- Các vi khuẩn gây nhiễm khuẩn bệnh viện: dịch tễ học lâm sàng, dịch tễ học phân tử, tính kháng thuốc của các vi khuẩn gây nhiễm khuẩn bệnh viện như MRSA, E. coli, Ps. aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii, E. coli, MRSA.
- Phát triễn các cơ sở dữ liệu khoa học, công cụ khai phá dữ liệu trên các nền tảng điện toán đám mây phục vụ nghiên cứu khoa học, khám và chữa bệnh.
ĐỀ TÀI KHOA HỌC
Cấp Trường | 5/2018 - 5/2019 | Đã nghiệm thu
Khảo sát tính kháng thuốc kháng sinh và một số đặc trưng về gen của các chủng Klebsiella pneumoniae gây nhiễm khuẩn tại Bệnh viện trường Đại học Y Dược Huế
CÔNG BỐ KHOA HỌC
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8. Ngo TMC, Ton Nu PA, Cao LC, Thuy Ha TN, Thao Do TB, Thi GT. A case of onychomycosis caused by a terbinafine-susceptible Fusarium solani in Vietnam. Iranian Journal of Microbiology. 2022. doi: 10.18502/ijm.v14i6.11269
9. Xuan Hai T, Thai Ngoc Minh N, Ngoc Anh D, Ngoc Dung T, Thi Minh Chau N, Tran-Anh L. A rare Fusarium equiseti infection in a 53-year-old male with burn injury: A case report. Current Medical Mycology. 2021. doi: 10.18502/cmm.7.1.6245
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2. Tam Chau HT, Ha Nguyen PN, Nguyen HB. Genotyping of Mycobacterium leprae strains in south central coast and central highlands of Vietnam. Iranian Journal of Microbiology. 2023. doi: 10.18502/ijm.v15i2.12470
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1. Giuliani C, Biggs D, Nguyen TT, et al. First evidence of association between past environmental exposure to dioxin and DNA methylation of CYP1A1 and IGF2 genes in present day Vietnamese population. Environmental Pollution. 2018;242:976-985. doi: 10.1016/j.envpol.2018.07.015
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3. Doro MG, Casu G, Frogheri L, et al. Molecular Characterization of β-Thalassemia Mutations in Central Vietnam. Hemoglobin. 2017;41(2):96-99. doi: 10.1080/03630269.2017.1321013
4. Fiamma M, Longoni SS, Ngo TMC, et al. Fasciolopsis buski infection in a Vietnamese pregnant woman with systemic lupus erythematosus. The Journal of Infection in Developing Countries. 2015;9(06):670-673. doi: 10.3855/jidc.7017
2. Nguyen TTU, Kim H, Chae YJ, Jung JH, Kim W. Serum VEGF-D level is correlated with renal dysfunction and proteinuria in patients with diabetic chronic kidney disease. Medicine. 2022;101(7):e28804. doi: 10.1097/MD.0000000000028804
4. Nguyen Thanh T, Nguyen Tran BS, Hoang Thi AP, et al. HER2Ile655Val Single Nucleotide Polymorphism Associated with Early-Onset Breast Cancer Susceptibility: A Systematic Review and Meta-Analysis. Asian Pacific Journal of Cancer Prevention. 2021;22(1):11-18. doi: 10.31557/apjcp.2021.22.1.11
5. Nguyen TTU, Yeom J, Kim W. Beneficial Effects of Vitamin E Supplementation on Endothelial Dysfunction, Inflammation, and Oxidative Stress Biomarkers in Patients Receiving Hemodialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. International Journal of Molecular Sciences. 2021;22(21):11923. doi: 10.3390/ijms222111923
6. Nguyen TTU, Kim HW, Kim W. Effects of Probiotics, Prebiotics, and Synbiotics on Uremic Toxins, Inflammation, and Oxidative Stress in Hemodialysis Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of Clinical Medicine. 2021;10(19):4456. doi: 10.3390/jcm10194456
7. Dang Cong T, Nguyen Thanh T, Nguyen Phan QA, Hoang Thi AP, Nguyen Tran BS, Nguyen Vu QH. Correlation between HER2 Expression and Clinicopathological Features of Breast Cancer: A Cross- Sectional Study in Vietnam. Asian Pacific Journal of Cancer Prevention. 2020;21(4):1135-1142. doi: 10.31557/APJCP.2020.21.4.1135
8. Nguyen VB, Nguyen VVH, Tran BT, Le CV, Dang CT, Baek JH. Undifferentiated pleomorphic sarcoma of the thyroid: A case report and ƚiterature review. Clinical Case Reports. 2020;8(4):680-684. doi: 10.1002/ccr3.2710
9. Truong V, Tran DT, Dang C. Collision occurrence of meningioma and astrocytoma: A case report and literature review. Asian Journal of Neurosurgery. 2019;14(3):938. doi: 10.4103/ajns.AJNS_97_19
1. Phan THG, Paliogiannis P, Nasrallah GK, et al. Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis. Cellular and Molecular Life Sciences. 2020;78(5):2031-2057. doi: 10.1007/s00018-020-03693-7
2. Pau MC, Pantaleo A, Tsamesidis I, et al. Clinical impact of the two ART resistance markers, K13 gene mutations and DPC3 in Vietnam. PLOS ONE. 2019;14(4):e0214667. doi: 10.1371/journal.pone.0214667